|
Fifty percent inhibition concentrations (IC50) and relative resistance of curcumin and cantharidin in sensitive and multidrug-resistant CEM leukemia tumor cell lines [16] |
||
| Curcumin |
Cantharidin |
|
|
|
||
| Growth inhibition assay: |
||
| CCRF-CEM |
30 μM |
20 μM |
| CEM/ADR5000 |
28 μM |
17 μM |
| Relative resistance |
0.9 |
0.9 |
| MTT-Assay: |
||
| CCRF-CEM |
>13.5 μM |
1.9 μM |
| CEM/VBL100 |
>13.5 μM |
1.4 μM |
| Relative resistance: |
n.d. |
1.4 |
| CEM/E1000 |
13.5 μM |
0.76 μM |
| Relative resistance |
n.d. |
0.4 |
|
n.d.: not determined | ||
Rauh et al. Chinese Medicine 2007 2:8 doi:10.1186/1749-8546-2-8 |
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