Table 1

Apparent permeability coefficient (Papp) of compounds 1, 2, 3 and D (n = 3)

Compound

*Pappat 53 μM

(10-6cm/s)

*Pappat 106 μM

(10-6cm/s)

P

Value


Compound 1

13.94 (0.60)

14.33 (0.17)

0.364

Compound 2

9.45 (0.29)

10.08 (0.32)

0.146

Compound 3

7.48 (0.31)**

8.60 (0.55)**

0.014

Compound D

8.53 (0.83)**

16.38 (0.61)**

0.001


*expressed as mean (SD), n = 3

**P < 0.05, significantly different between these two concentrations.

Tangyuenyongwatana et al. Chinese Medicine 2009 4:19   doi:10.1186/1749-8546-4-19

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