Table 1 |
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|
Summary of results from single herb ginseng clinical trials |
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|
Trial quality* |
Research topic |
Participants (n) |
Herb species |
Chinese medicine theory |
Reference |
|
|
|
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|
Negative results |
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|
Allen JD et al. (1998) |
4 |
Exercise performance |
Healthy young (28) |
P. ginseng |
No Qi-deficiency |
[17] |
|
Cardinal BJ et al. (2001) |
4 |
Psychological well-being |
Healthy young adults (83) |
P. ginseng |
No Qi-deficiency |
[18] |
|
Caron MF et al. (2002) |
3 |
Cardiovascular function |
Healthy adults (30) |
P. ginseng |
No Qi-deficiency |
[42] |
|
Dowling EA et al. (1996) |
3 |
Exercise performance |
Highly trained distance runners (20) |
Acanthopanax senticosus |
No Qi-deficiency |
[43] |
|
Engels HJ et al. (1997) |
3 |
Physiologic and psychological responses |
Healthy adults (36) |
P. ginseng |
No Qi-deficiency |
[21] |
|
Engels HJ et al. (2001) |
3 |
Exercise & short-term recovery |
Healthy active women (24) |
P. ginseng |
No Qi-deficiency |
[20] |
|
Engels HJ et al. (2003) |
3 |
Physical performance heart rate recovery |
Active healthy adults (38) |
P. ginseng |
No Qi-deficiency |
[19] |
|
Stavro PM et al. (2006) |
3 |
Blood pressure and renal function |
Hypertension (52) |
P. quinquefolius |
Inappropriate herb species |
[49] |
|
Wiklund IK et al. (1999) |
N/A |
Quality of life & physiological parameters |
Symptomatic postmenopausal women (384) |
P. ginseng |
Inappropriate herb species |
[51] |
|
Positive results |
||||||
|
Cicero AF et al. (2004) |
2 |
Quality of life |
Elderly hypertensive and digitalized (20) |
Acanthopanax senticosus |
Appropriate herb species |
[53] |
|
de Andrade E et al. (2007) |
2 |
Sexual function |
Erectile dysfunction (60) |
P. ginseng |
Qi-Deficiency |
[44] |
|
Ellis JM et al. (2002) |
5 |
Quality of life |
Healthy young (30) |
P. ginseng |
Marginal Qi-deficiency |
[48] |
|
Gross D et al. (2002) |
N/A |
Respiratory function |
Chronic Obstructive Pulmonary Disease (COPD) (92) |
P. ginseng |
Qi-Deficiency |
[22] |
|
Hong B et al. (2002) |
3 |
Sexual function |
Erectile dysfunction (45) |
P. ginseng |
Qi-Deficiency |
[45] |
|
Kim JH et al. (2006) |
3 |
Quality of life |
Cancer (53) |
P. ginseng |
Qi-Deficiency |
[23] |
|
Liang MT et al. (2005) |
3 |
Endurance exercise |
Untrained adults (29) |
P. notoginseng |
Appropriate herb species |
[54] |
|
McElhaney JE et al. (2004) |
3 |
Acute respiratory illness |
Sub healthy seniors(198) |
P. quinquefolius |
Qi-Deficiency |
[24] |
|
McElhaney JE et al. (2006) |
5 |
Acute respiratory illness |
Sub healthy adults and seniors (43) |
P. quinquefolius |
Qi-Deficiency |
[46] |
|
Predy GN et al. (2005) |
5 |
Cold |
Sub healthy adults (323) |
P. quinquefolius |
Qi-Deficiency |
[25] |
|
|
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|
*Trial quality evaluation scale [47] 0–2: poor quality 3–5: high quality N/A: full text unavailable for quality evaluation |
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|
Yan et al. Chinese Medicine 2009 4:3 doi:10.1186/1749-8546-4-3 |
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