Table 2

Relative uterotrophic and anti-uterotrophic activities

ERr 731 (μg/kg BW/d)

Estradiol (mg/kg BW/d)

0

0.5

4

0

100

211.5 ± 42.7***

576.6 ± 220***/623.8 ± 35.6***

0.1

75.5 ± 9.2/97.3 ± 24.9

189.3 ± 46.1***

-/-

1

85 ± 8.7

162.8 ± 35.1***

-/-

10

103.3 ± 15.2

182.5 ± 31.7***

-/-

100

122.9 ± 13.7/104.2 ± 19.6

130 ± 18.1*/⁺⁺

-/-

Note:

The mean ± SD of uterine wet weights expressed as percentage of untreated controls are shown. If two values are shown, they represent means ± SD from two independent experiments.

*P < 0.05, ***P < 0.001: statistical significance (Student's t-test) if compared to untreated controls

⁺⁺P < 0.01: statistical significance (Student's t-test) if compared to low dose estradiol treatment (0.0005 mg/kg BW/d)

Vollmer et al. Chinese Medicine 2010 5:7   doi:10.1186/1749-8546-5-7